Collaborations in progress
The Keeping Children Safe at Home (KCS) study is a 5-year multicentre collaborative programme of research to prevent home injury in pre-school children, funded by a programme grant from the National Institute for Health Research.
It is being led by the University of Nottingham (Professor Denise Kendrick, Dr Carol Coupland, Dr Michael Watson) and collaborators include the University of the West of England (Dr Toity Deave and formerly Professor Elizabeth Towner), Newcastle University (Professor Elaine McColl), Norfolk and Norwich University Hospitals NHS Foundation Trust (Dr Richard Reading), Leicester University (Professor Alex Sutton and Dr Nicola Cooper), Child Accident Prevention Trust (Dr Mike Hayes), Nottinghamshire Healthcare NHS Trust (Ms Jane Stewart, Ms Jo Wain, Ms Rose Clacy), Nottingham University Hospitals NHS Trust (Mr Frank Coffey), and Dr Emma Pitchforth.
This study aims to improve understanding of how to prevent falls, poisoning and thermal injuries in children under 5 years in order to increase evidence based injury prevention within the NHS. The programme of work includes a number of inter-related studies. The information from these studies will be used to determine the cost effectiveness of different injury interventions. Finally, the study will develop injury prevention briefings (IPBs) for cost effective interventions and evaluate the implementation of one IPB in Children’s Centres across the UK. The study commenced in April 2009 and is funded for 5 years.The programme comprises 14 studies addressing the following research questions, all of which relate to falls, poisoning and thermal injuries:
The findings from these studies will be used to enhance evidence-based injury prevention in the NHS. The potential impacts of this research are reductions in injury occurrence, injury inequality, health care use and its associated costs.
Further information about this project can be found here.
Papers and reports associated with this study
Ablewhite J, McDaid L, Hawkins A, Peel I, Goodenough T,
T, Stewart J, Watson M, Kendrick D. Approaches
used by parents to keep their children safe at home: a
qualitative study to explore the perspectives of parents with children
aged under five years. BMC Public Health 2015,
Ablewhite J, Peel I, McDaid L, Hawkins A, Goodenough T, Deave T, Stewart J, Kendrick D. Parental perceptions of barriers and facilitators to preventing child unintentional injuries within the home: a qualitative study. BMC Public Health 2015; 15: e280. doi:10.1186/s12889-015-1547-2.
Achana FA, Cooper NJ, Bujkiewicz S, Hubbard SJ, Kendrick D, Jones DR, Sutton AJ. Network meta-analysis of multiple outcome measures accounting for borrowing of information across outcomes. BMC Medical Research Methodology 2014;14:92. doi:10.1186/1471-2288-14-92.
Achana FA, Cooper NJ, Dias S, Lu G, Rice SJ, Kendrick D, Sutton AJ. Extending methods for investigating the relationship between treatment effect and baseline risk from pairwise meta-analysis to network meta-analysis. Stat Med. 2013 Feb 28:32(5):752-71 doi:10.1002/sim.5539. Epub 2012 Aug2.
Achana F, Hubbard S, Sutton A, Kendrick D, Cooper N. An exploration of synthesis methods in public health evaluations of interventions concludes that the use of modern statistical methods would be beneficial. Journal of Clinical Epidemiology 2014;67:376-390. doi: 10.1016/j.jclinepi.2013.09.018.
Achana FA, Sutton AJ, Kendrick D, Hayes M, Jones D, Hubbard SJ, Cooper NJ. A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children. BMC Public Health (In press)
Achana FA, Sutton AJ, Kendrick D, Wynn P, Young B, Jones DR, Hubbard SJ, Cooper NJ. The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis. PLoS One 2015; 10: e0121122. doi:10.1371/journal.pone.0121122
Cooper NJ, Kendrick D, Achana F, Dhiman P, He Z, Wynn P,Le Cozannet E, Saramago P, Sutton AJ. Network Meta-analysis to Evaluate the Effectiveness of Interventions to Increase the Uptake of Smoke Alarms. Epidemiologic Reviews. 2012. 34. doi:10.1093/epirev/mxr015.
Cooper NJ, Kendrick D, Timblin C, Hayes M, Masjak-Newman G, Meteyard K, Hawkins A, Kay B. The short-term cost of falls, poisonings and scalds occurring at home in children under 5 years old in England: multicentre longitudinal study. Inj Prev. 2016; 22:334-341 doi:10.1136/injuryprev-2015-041808.
Deave T, Goodenough T, Stewart J, Towner E, Majsak-Newman G, Hawkins A, Coupland C, Kendrick D. Contemporary hazards in the home: keeping children safe from thermal injuries. Arch Dis Child. 2013 Jul;98(7):485-9. doi:10.1136/archdischild-2012-302901.
Deave T, Hawkins A, Kumar A, Cooper N, Goodenough T, Watson M, Coupland C, Majsak-Newman G, Mcdaid L, Ablewhite J, Clacy R, McColl E, Reading R, Hayes M, Kendrick D. Implementation of a fire-prevention injury prevention briefing in children's centres: a multicentre cluster-randomised controlled trial (Meeting abstract). The Lancet, Volume 384, Page S6, 19 November 2014. doi:10.1016/S0140-6736(14)62132-2.
Deave T, Hawkins A, Kumar A, Hayes M, Cooper N, Watson M, Ablewhite J, Coupland C, Sutton A, Majsak-Newman G, McDaid L, Goodenough T, Beckett K, McColl E, Reading R, Kendrick D. Evaluating implementation of a fire-prevention injury prevention briefing in children’s centres: Cluster randomised controlled trial. PLoS ONE 2017 12(3):e0172584. https://doi.org/10.1371/journal.pone.0172584
Deave T, Towner EML, McColl E, Reading R, Sutton A, Coupland CAC, Cooper N, Stewart J, Hayes M, Pitchforth E, Watson M, Kendrick D. Multicentre cluster randomised controlled trial evaluating implementation of a fire-prevention injury prevention briefing in children's centres: Study protocol. BMC Public Health 2014; 14(1): 69.
Hayes M, Kendrick D. Guide for Commissioners of child health
preventing unintentional injuries among the under fives.
Nottingham: Nottingham University, 2016.
Hayes M, Kendrick D, Deave T. Injury Prevention Briefing. Preventing unintentional injuries to the under fives: a guide for practiitoners. Nottingham: Nottingham University, 2014. *
Z, Wynn P, Kendrick D. Non-resuscitative first-aid training for
lay people: a systematic review. Journal of Emergency
Hindmarch P, Hawkins A, McColl E, Hayes M, Majsak-Newman G, Ablewhite J, Deave T, Kendrick D on behalf of the Keeping Children Safe study group. Recruitment and retention strategies and the examination of attrition bias in a randomised controlled trial in children's centres serving families in disadvantaged areas of England. Trials 2015, 16:79. doi:10.1186/s13063-015-0578-4.
Hubbard S, Cooper N, Kendrick D, Young B, Wynn PM, He Z, Miller P, Achana F, Sutton A. Network meta-analysis to evaluate the effectiveness of interventions to prevent falls in children under age 5 years. Injury Prevention 2014;67:376-390. doi:10.1136/injuryprev-2013-041135.
Ingram JC, Deave T, Towner E, Errington G, Kay B, Kendrick D. Identifying facilitators and barriers for home injury prevention interventions for pre-school children: a systematic review of the quantitative literature. Health Educ Res. 2012 Apr; 27(2):258-68. doi: 10.1093/her/cyr066.
Kendrick D, Majsak-Newman G, Benford P, Coupland C, Timblin C, Hayes M, Goodenough T, Hawkins A, Reading R. Poison prevention practices and medically attended poisoning in young children: multicentre case–control study. Inj Prev. Published Online First: 4 Nov 2016, doi:10.1136/injuryprev-2015-041828.
Kendrick D, Maula A, Reading R, Hindmarch P, Coupland C, Watson M, Hayes M, Deave T. Risk and Protective Factors for Falls From Furniture in Young Children. Multicenter Case-Control Study. JAMA Pediatr. Published online December 01, 2014. doi:10.1001/jamapediatrics.2014.2374.
Kendrick D, Maula A, Stewart J, Clacy R, Coffey F, Cooper N, Coupland C, Hayes M, McColl E, Reading R, Sutton A, Towner EM, Watson MC; Keeping Children Safe Study Group. Keeping children safe at home: protocol for three matched case-control studies of modifiable risk factors for falls. Inj Prev. 2012 Jun;18(3):e3. doi: 10.1136/injuryprev-2012-040394.
Kendrick D, Young B, Mason-Jones AJ, Ilyas N, Achana FA, Cooper NJ, Hubbard SJ, Sutton AJ, Smith S, Wynn P, Mulvaney C, Watson MC, Coupland C. Home safety education and provision of safety equipment for injury prevention. Cochrane Database of Systematic Reviews 2012, Issue 9. Art. No.: CD005014. DOI: 10.1002/14651858.CD005014.pub3.
Kendrick D, Young B, Mason-Jones AJ, Ilyas N, Achana FA, Cooper NJ, Hubbard SJ, Sutton AJ, Smith S, Wynn P, Mulvaney CA, Watson MC, Coupland CAC. Home safety education and provision of safety equipment for injury prevention (Review). Evid. Based Child Health 2013; 8(3): 761-939.
Kendrick D, Zou K, Ablewhite J, Watson
C, Kay B, Hawkins A, Reading R. Risk and protective factors for falls
on stairs in young children: multi-centre case-control study.
Archives of Disease in Childhood. Online First, published on December
10, 2015 as
Majsak-Newman G, Benford P, Ablewhite J, Clacy R, Coffey F, Cooper N, Coupland CAC, Hayes M, Kay B, McColl E, Reading R, Sutton A, Stewart J, Watson MC, Kendrick D. Keeping children safe at home: protocol for a matched case-control study of modifiable risk factors for poisoning. Inj. Prev. 2014; ePub(ePub): ePub.
Saramago P, Sutton AJ, Cooper NJ, Manca A. Mixed treatment comparisons using aggregate and individual participant level data. Stat Med. 2012 Dec 10; 31(28):3516-36. doi: 10.1002/sim.5442. Epub 2012 Jul 5.
Watson M, Benford P, Clacy R et al. Validation of a home safety questionnaire used in a series of case-control studies. Inj Prev. Published Online First: 3 March 2014. doi:10.1136/injuryprev-2013-041006.Watson MC, Mulvaney C, Kendrick D, Stewart J, Coupland C, Hayes M, Wynn P, on behalf of the Keeping Children Safe at Home programme. National survey of the injury prevention activities of sure start children's centres. Inj Prev 2012, 18, A103.
Watson MC, A Mulvaney C, Kendrick D, Stewart J, Coupland C, Hayes M, Wynn P; Keeping Children Safe programme team. National survey of the injury prevention activities of children's centres. Health & Social Care in the Community, Volume 22, Issue 1, pages 40–46, January 2014.
Mulvaney C, Timblin
C, Stewart J, Coupland C, Deave T, Hayes M, Kendrick D.
opportunities to keep children safe?
National survey of injury prevention activities of children's
centres. Health Education Journal, 75(7), 833-842, 2016. doi:
Wynn P, Stewart J, Kumar A, Clacy R, Coffey F, Cooper N, Coupland CAC, Deave T, Hayes M, McColl E, Reading R, Sutton A, Watson M, Kendrick D. Keeping children safe at home: protocol for a case-control study of modifiable risk factors for scalds. Inj. Prev. 2014; ePub(ePub): ePub.
PM, Zou K, Young B, Majsak-Newman G, Hawkins A, Kay B, Mhizha-Murira J,
Kendrick D. Prevention
poisoning in the home: overview of systematic reviews and a systematic
review of primary studies.
Int. J. Inj. Control Safe. Promot. 2015; ePub(ePub): ePub. doi:
Zou K, Wynn PM, Miller P, Hindmarch P, Majsak-Newman G, Young B, Hayes M, Kendrick D. Preventing childhood scalds within the home: overview of systematic reviews and a systematic review of primary studies. Burns. 2015 Apr 1. pii: S0305-4179(14)00371-4. doi:10.1016/j.burns.2014.11.002
* This briefing supports
some of the recommendations around strategies, activities, education
and training for practitioners in the NICE guideline on preventing
unintentional injuries and around prioritisation and home
in the NICE guideline on preventing
unintentional injuries in the
Page revision date: 16 June